AnyGenes: signaling pathways and biomarkers profiler

Efficient 2019-nCOV detection kit, one step RT-qPCR (2 targets)

NEW !

Developed following the Emergency Use Authorization from the FDA

- Specific detection of the 2019-nCOV strain (covid-19)

- No detection of other related coronavirus strains

- Based on BHQ quencher (Black Hole Quencher®)

- Lyophilized 96 RT-qPCR array assays

- Other formats under request

Hyperinflammation and Immune System SingArray

NEW !

Beside 2019-nCOV assay, discover a complementary tools to analyze covid-19 pandemic in our catalog

SignArray tool based on 84 factors of hyperinflammation and immune system trigged by SARS-CoV-2 virus (IL2, IL6, IL7, IL8, IL9, IL10, IL1B, IL12B, IL15, IL23A, TNF, MCP1, CCL2, CCL3, CCL4, CXCL12....)

Larg catalog of signaling pathways ready to use, to analyze COVID-19 mechanism

YOUR FAVOURITE SIGNALING PATHWAYS!
SPEND LESS MONEY AND GET MORE RESULTS!

You can find any Signaling Pathways for Human, Mouse, Rat and any species at very competitive prices

ALL IN ONE SOLUTION SIGNARRAYS® SYSTEM

Epigenetic regulation ( Newsletter 03/17 )

How epigenetic factors can modify the cell fate and be actively involved in carcinogenesis.

Analyse any genes or panel of genes for any species at very competitive prices

- Experimentally validated
- Totally customizable
- Perfect for many applications

Discover now our Validated Primer Sets !

NEW !

Analyse more Signaling Pathways from few biological material (5ng) thanks to our cDNA preamplification SpeAmpn Kits!

Analyse your microbiota profile at very competitive prices with our new range of experimentally validated microbiota assays and SignArrays!

News

1- BIO-Europe Spring 2020

AnyGenes will be present at BIO-Europe Spring 2020

2- AnyGenes products and services in JAPAN

We are proud to have signed an agreement with the company Funakoshi, Co, Ltd, for the distribution of AnyGenes products and services in JAPAN

3- BIOFIT 2018, LILLE, 4-5 December

AnyGenes team will be present at BioFIT Event 2018 at Lille, FRANCE

4- Specific Pre-amplification kit

You have small quantity of biological sample but many signaling pathways to explore? AnyGenes® team is proud to help you with our new range of cDNA pre-amplification SpeAmpⁿ system to perform high-throughput analysis with very small amounts of biological material (5 ng RNA) or few cells.

5- MEDICA 2017/ Dûsseldorf, GERMANY, 13-16 NOV

AnyGenes® team was present at MEDICA 2017, the key world forum for medicine. AnyGenes® stays informed of all the news, innovative projects, latest technologies and issues in medical fields in order to offer you innovative products and tools.

6- BioJapan/ Regenerative Medicine Japan 2016

AnyGenes® has been selected by the EU-Japan centre, for BtoB meetings at Osaka from 9-11 October, and to present its products (SignArrays®) and its multi-biomarkers clinical tests at BioJapan 2016, October 12-14, Yokohama, JAPAN.

7- Chinese Medicine Conference 2016

Dr Ju Liya has held a conference at the 2nd World Forum on Astragalus membranaceus, 10 June 2016 at Beijing CHINA. Dr Ju Liya had talked about interesting results from in vitro analysis of compounds from chinese medicine by using AnyGenes® molecular platform.

8- Products

Discover now our various signaling pathways (SignArrays®) and Highly sensitive and specific assay kits for specific gene quantification by real time qPCR array.

Please see some of scientific publications with our products

1. Buart S et al. Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3. Oncotarget (2017) 8(65): 108786-108801.

2. Broséus J et al. VEGF121, is predictor for survival in activated B-cell-like diffuse large B-cell lymphoma and is related to an immune response gene signature conserved in cancers. Oncotarget. (2017) 8(53): 90808-90824.

3.Delyon J et al. PDE4D promotes FAK-mediated cell invasion in BRAF-mutated melanoma. Oncogene (2017) 36(23): 3252-3262.

4. Doucet M et al. Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking. Biopreserv Biobank (2017) 15(3): 270-276.

5. Delyon J et al. Validation of a preclinical model for assessment of drug efficacy in melanoma. Oncotarget (2016) 7(11): 13069-13081.

6. Xu-Dubois YC et al. Markers of endothelial to mesenchymal transition: evidence for antibody-endothelium interaction during antibody mediated rejection in kidney recipients. J Am Soc Nephrol. (2016) 27(1): 324-332.

7. Mourah S et al. Dramatic Transient Improvement of Metastatic BRAFV600E-Mutated Langerhans Cell Sarcoma under treatment with Dabrafenib. Blood (2015) 126(24): 2649-2652.

8. Delyon J et al. EMMPRIN regulates β1 integrin-mediated adhesion through Kindlin-3 in human melanoma cells. Exp Dermatol (2015) 24(6): 443-448.

9. Khayati F et al. EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF. Oncotarget (2015) 6(12): 9766-9780.

10. Ranchoux B et al. Endothelial-to-mesenchymal transition in pulmonary hypertension. Circulation (2015) 131(11): 1006-1018.

11. Djaafri I et al. A novel tumor suppressor function of Kindlin-3 in solid cancer. Oncotarget (2014) 5(19): 8970-8985.

12. Milia-Argeiti E et al. EMMPRIN/CD147-encriched membrane vesicles released from malignant human testicular germ cells increase MMP production through tumor-stroma interaction. Biochim. Biophys. Acta (2014) 1840(8): 2581-2588.

13. Lescaille G et al. EMMPRIN/CD147 up-regulates urokinase-type plasminogen activator: implications in oral tumor progression. BMC Cancer (2012) 12(115): 1-9.

14. Milia-Argeiti E et al. Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours. Int. J. Androl (2012) 35(6): 835-844.

15. Huet E et al. EMMPRIN Modulates Epithelial Barrier Function through a MMP-Mediated Occludin Cleavage : Implications in Dry Eye Disease. Am. J. Pathol. (2011) 179(3): 1278-1286.

16. Moreau M et al. b-Catenin and NF-κB cooperate to regulate the uPA/uPAR system in cancer cells. Int. J. Cancer (2011) 128(6): 1280-1292.

17. Bougatef F et al. EMMPRIN Promotes Melanoma Cells Malignant Properties through a HIF-2alpha Mediated Up-Regulation of VEGF-Receptor-2. PLoS One (2010) 5(8): e12265.

18. Paule B et al. Soluble Isoforms of Vascular Endothelial Growth Factor Are Predictors of Response to Sunitinib in Metastatic Renal Cell Carcinomas. PLoS One (2010) 5(5): e10715.

19. Ma L et al. Antisense Inhibition of Amphiregulin Expression Reduces EGFR Phosphorylation in Transformed Human Breast Epithelial Cells. Anticancer Res. (2010) 30(6): 2101-2106.

20. Bougatef F et al. EMMPRIN promotes angiogenesis through hypoxia-inducible factor-2-mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2. Blood (2009) 114(27): 5547-5556.

Signaling Pathways

qPCR Master Mixes

Pre-Amplification Kits NEW!

Validated Primer Sets

Biomarker Platform Services

Microbiota AssaysNEW!